Ventricles & Choroid Plexus
Ventricles:
- The ventricles consist of four hollow, fluid filled spaces inside the brain.
- These ventricles are lined by a specialized type of glial cell called ependymal cells, or the ependyma.
- The innermost layer of the meninges, called the pia mater, forms invaginations in some parts of the ventricles.
- These vascularized invaginations, are lined by a plexus of specialised cells that produce our CSF.
- This plexus of cells is called the choroid plexus.
- The ventricular system is a set of four interconnected cavities (ventricles) in the brain and the location of CSF production.
- This system is continuous with the central canal of the spinal cord. The system comprises four ventricles:
- right and left lateral ventricles (the first and second ventricles)
- third ventricle
- fourth ventricle
Lateral ventricles or Paracoel:
- The two lateral ventricles are located in the brain parenchyma, one in each cerebral hemisphere.
- The lateral ventricles are roughly C shaped.
- They consist of a body with an anterior, a posterior (occipital) and an inferior (temporal) horn.
- The body of the ventricle passes through the parietal lobe and into the frontal lobe.
- Each lateral ventricle is connected to the third ventricle by an interventricular foramen (foramen of Monro).
- Septum Pellucidum is present between two lateral ventricles
Third ventricle or Diocoel:
- The third ventricle is a narrow (unpaired) cavity that lies between the cerebral hemispheres.
- Specifically, this ventricle lies in the diencephalon where it is enclosed laterally by the hypothalamus and thalamus.
- The third ventricle is connected to the fourth ventricle through the cerebral aqueduct (aqueduct of Sylvius).
Fourth Ventricle or Myelocele:
- The fourth ventricle is diamond-shaped and lies at the level of the brainstem, specifically within the pons or in the superior portion of the medulla.
- The fourth ventricle is continuous with the central canal of the spinal cord.
- Two Lateral apertures (foramina of Luschka), and one median aperture (foramen of Magendie) in the roof of the fourth ventricle facilitates the exiting flow of CSF to the subarachnoid space that surrounds the brain and spinal cord.