- The posterior pituitary is actually an extension of the neurons of the hypothalamus.
- It comprises of 25% part of pituitary
- The cell bodies of these regions rest in the hypothalamus, but their axons descend as axon terminals in the posterior pituitary
- The axon terminals are embedded in a neuroglial tissue formed of cells known as pituicytes
- The posterior pituitary gland does not produce hormones, but rather stores and secretes hormones produced by the hypothalamus.
- These hormones are stored in small vesicles in the axons and terminals called Herring bodies.
Hormones released from Posterior Lobe:
1. Oxytocin:
- This hormone is produced by Paraventricular nuclei in the hypothalamus and is stored in posterior pituitary
- This hormone stimulates the contraction of smooth muscles of the uterus in pregnant women and causes easy childbirth.
- It also contracts the smooth muscles of mammary glands in lactating mothers and facilitates the flow of milk at the time of suckling
- Thus it is known as 'Birth hormone' or 'Milk Ejecting Hormone'
- Artificial Oxytocin is given to induce labour pain during parturition and this is known as Pitocin
- Oxytocin also stimulates the relaxation of the gallbladder, urinary bladder and intestine.
2. Vasopressin or Antidiuretic Hormone (ADH):
- This is produced by Supraoptic nuclei in the Hypothalamus and is stored in posterior pituitary
- The primary function of vasopressin is to increase reabsorption of water in the distal convoluted tubules and collecting tubules of the kidney.
- So its deficiency in body increases the volume of urine causing diabetes insipidus.
- This type of diabetes is different from diabetes mellitus as in this the urine is free from sugar.
- Another important function of ADH is to bring about contraction of smooth muscles of the intestine, gallbladder, urinary bladder and blood vessels.
- Hence, large quantities of the hormone cause the arterial blood pressure to rise due to the contraction of peripheral, arterioles.
- Intake of alcohol reduces ADH secretion.