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Antibodies : Structure and Classification - Practice Questions & MCQ
Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET
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Antibodies is considered one of the most asked concept.
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Antibodies
- Antibodies are glycoproteins formed in response to antigenic stimulation and counteract with antigens with great specificity.
- The antibodies are found in the serum fraction of the blood and are also known as immunoglobulins (Ig).
- Each antibody molecule has four peptide chains, two small called light chains and two longer called heavy chains.
- Hence, an antibody is represented as H2L2.
- Each light-chain contains a single variable-domain and a single constant-domain.
- Each heavy-chain contains a singly variable-domain and three, sometimes, four constant-domains.
- Variable (V) regions of both the chains lie opposite to each other at the top of the two arms of the antibody molecule and represent the site where the antigen-antibody-binding takes place.
- According to their physicochemical properties, the immunoglobulins are subdivided into five different classes, namely, IgG, IgA, IgM, IgD, and IgE.
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