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Humoral Immunity or Antibody Mediated Immunity MCQ - Practice Questions with Answers
Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET
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Humoral Immunity or Antibody Mediated Immune System (AMIS) is considered one of the most asked concept.
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Humoral Immunity or Antibody Mediated Immune System (AMIS)
- Antibodies are the specialized proteins produced in the body in response to antigen that circulate in the body fluids like blood plasma and lymph.
- Since, the word ‘humor’ pertains to fluid and these antibodies are found in the fluids, the response is also called humoral immune response.
- В-lymphocytes (B-cells) produce antibodies that regulate humoral immunity.
- The T-lymphocytes themselves do not secrete antibodies but help В lymphocytes produce them.
- Humoral immunity or antibody-mediated immune system (AMIS) provides defense against most extracellular bacterial pathogens and viruses that infect through the respiratory and intestinal tract.
- When antibodies on В-cells surface bind antigens (any substances that cause antibodies formation) the В cell is activated and divides, producing a clone (descendants of a single cell) of daughter В cells.
- These clones give rise to plasma В-cells and memory В-cells.
- Some of the activated В cells enlarge, divide and differentiate into a clone of plasma B-cells.
- Although plasma cells live for only a few days, they secrete enormous amounts of antibody during this period.
- Some activated В-cells do not differentiate into plasma cells but rather remain as memory B-cells (Primed cells).
- They have a longer life span. The memory cells remain dormant until activated once again by a new quantity of the same antigen.
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