Nerve Impulse
- All the nerve fibres carry information in the form of the nerve impulse.
- The nerve impulse is the sum total of physical and chemical disturbances created by a stimulus (electrical, chemical or mechanical) in a neuron or nerve fibre which results in the movement of a wave along the nerve fibre.
- The nerve fibre or axon is like a cylinder.
- The interior of the axon is filled with axoplasm (i.e., the cytoplasm of the nerve cell)
- The exterior of the axon is covered with a thin membrane, the axon membrane or axolemma.
- Axolemma is selectively permeable for simple organic and inorganic molecules
- The axon is immersed in the extracellular fluid (ECF).
- Through axolemma movement of solute takes place between the axoplasm and ECF.
- Generally, the solutes in ECF and axoplasm are in ionic form.
Membrane or Ionic Theory of Nerve Impulse:
- It was proposed by Hodgkin and Huxley in the 1930s.
- This theory suggests that the electrical events in the nerve fibres are governed by differential permeability of the axolemma to sodium and potassium ions.
- The differential permeability is regulated by the electric field across the membrane.
- As per this theory, the conduction of nerve impulse can be categorised into two phases:
- Resting membrane potential of nerve
- Action membrane potential of nerve