NEET Sample Paper 2025 PDF by NTA - Model Question Paper With Solution

Mechanism of Hormone Action MCQ - Practice Questions with Answers

Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET

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  • 13 Questions around this concept.

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The secondary messenger in peptide hormone action is

 

Which of the following hormones given below would have intracellular receptors?

Which of the following hormones can activate both G protein-coupled receptors and intracellular receptors?

NEET 2025: SyllabusMost Scoring concepts NEET PYQ's (2015-24)

NEET PYQ's & Solutions: Physics | ChemistryBiology

 Intracellular receptors are mostly

 

In the mechanism of action of a protein hormone, one of the second messengers is
 

Concepts Covered - 1

Mechanism of Hormone Action
  • The hormones can be of two types:
    • Water-soluble, such as amino acid derivatives, peptide hormones and protein hormones
    • Lipid soluble, such as steroid hormones
  • The water-soluble hormones need an extracellular receptor and a secondary messenger for carrying out their activity.
  • Lipid soluble hormones can act directly on the DNA.

Mode of Protein Hormone Action through Extracellular Receptors:

  • Hormones produce their effects on target tissues by binding to specific proteins called hormone receptors located in the target tissues only.
  • The hormone-receptor complex induces the release of GDP from the G protein.
  • The α- subunit bearing GTP separates from the combined β and у subunits. The β and у subunits do not separate from each other. 
  • The activated β and γ subunits of G protein activate adenyl cyclase. 
  • The activated adenyl cyclase catalyses the formation of cyclic adenosine monophosphate (cAMP) from ATP.
  • The hormone is called the first messenger and cAMP is termed the second messenger.
  • Amplification of the signal through a cascade effect.

Mode of Steroid Hormone Action through Intracellular Receptors:

  • Steroid hormones are lipid-soluble and easily pass through the cell membrane of a target cell into the cytoplasm. 
  • In the cytoplasm, they bind to specific intracellular receptors (proteins) to form a hormone-receptor complex that enters the nucleus.
  • In the nucleus, they regulate gene expression or chromosome function.
     

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Mechanism of Hormone Action

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