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Replication of DNA MCQ - Practice Questions with Answers
Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET
Quick Facts
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Introduction to Replication of DNA is considered one of the most asked concept.
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11 Questions around this concept.
Solve by difficulty
Semi-conservative replication of DNA was first demonstrated in:
The experimental proof for semiconservative replication of DNA was first shown in a
Match the following in most appropriate way:
|
Parts |
Layers |
|
A.Helicase |
(i). Connect small fragments |
|
B.Polymerase |
(ii). Disrupts H-bond |
|
C.Ligase |
(iii). Create a new strand |
|
D.Primase |
(iv). Create RNA sequence |
NEET 2025: Syllabus | Most Scoring concepts | NEET PYQ's (2015-24)
Watson and Crick (1953) proposed DNA double helix model and won the Nobel Prize; their model of DNA was based on
- X-ray diffraction studies of DNA done by Wilkins and Franklin
- Chargaff’s base equivalence rule
- Griffith’s transformation experiment
- Meselson and Stahl’s experiment.
DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the
Concepts Covered - 1
Introduction to Replication of DNA
- Genetic information present in double-stranded DNA molecules is transmitted from one cell to another cell at the time of mitosis and from parent to progeny by faithful replication of parental DNA molecules.
- The scheme suggested by Watson and Crick provided that the two strands would separate and act as a template for the synthesis of new complementary strands.
- After the completion of replication, each DNA molecule would have one parental and one newly synthesized strand.
- This scheme was termed as semiconservative DNA replication.
- Several mechanisms of DNA replication were proposed by scientists:
- The conservative model of DNA replication holds that when DNA is replicated prior to cell division, one of the DNA double-strands receives all newly replicated DNA in both strands, while the other receives only the two original DNA strands in the parent cell.
- The semi-conservative model (also called the "zipper model" by James Watson), holds that the original two strands of DNA are split from each other and that the two daughter molecules are each comprised of one "old" strand of DNA from the parent cell, and one newly replicated strand.
- The dispersive model holds that the DNA is copied in short stretches and that both daughter DNA strands will receive a mixture of the original parental DNA and newly replicated DNA.
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