The following family tree traces the occurrence of a rare genetic disease. The filled symbols signify the individuals with the disease, whereas the open symbols signify healthy individuals

Based on this information, the disease is most likely to be

(A) Autosomal, dominant (B) Autosomal, recessive

(A)

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(B)

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(C)

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(D)

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In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree.

X-linked recessive

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Autosomal recessive

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X-linked dominant

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Autosomal dominant

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Which of the following occurs due to the presence of an autosome-linked dominant trait?

Myotonic dystrophy

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Haemophilia

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Thalassemia

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Sickle cell anaemia

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Study the pedigree chart of a certain family given below and select the correct conclusion which can be drawn for the character

The female parent is heterozygous

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The female parent could not have had a normal daughter for this character

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The trait under study could not be colour blindness

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The male parent is homozygous dominant

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Autosomal ________ inheritance is a way a genetic trait or condition can be passed down from parent to child.

Dominant

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Recessive

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Both (a) and (b)

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None of the above.

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Concepts Covered - 0

Determining the inheritance pattern of autosomal recessive disorder

The autosomal recessive disorder would be shown by those individuals who have two copies of the disease-causing recessive allele.
An individual with a single copy of disease-causing recessive allele would be the carrier for the disease.
Parents of an affected individual have to be carriers, that is, heterozygous for the disease-causing recessive allele. They are unaffected but can pass the disorder.
When parents are heterozygous, one-fourth of the progeny will be affected.
Autosomal recessive disorders tend to skip generations.
It appears in males and females with equal frequency.

Determining the inheritance pattern of autosomal dominant disorder:

The autosomal recessive disorder would be shown by those individuals who have even a single copy of the disease-causing dominant allele.
There are no carriers/heterozygotes for autosomal dominant disorders.
It appears in both the sexes with an equal frequency.
The disease does not skip a generation.
When one parent is affected and the other one is unaffected, one-half of the offsprings will be affected by the autosomal dominant disease.
Unaffected parents do not pass the disorder.