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Autosomal Dominant & Recessive inheritance pattern - Practice Questions & MCQ
Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET
Concepts Covered - 0
Determining the inheritance pattern of autosomal recessive disorder
- The autosomal recessive disorder would be shown by those individuals who have two copies of the disease-causing recessive allele.
- An individual with a single copy of disease-causing recessive allele would be the carrier for the disease.
- Parents of an affected individual have to be carriers, that is, heterozygous for the disease-causing recessive allele. They are unaffected but can pass the disorder.
- When parents are heterozygous, one-fourth of the progeny will be affected.
- Autosomal recessive disorders tend to skip generations.
- It appears in males and females with equal frequency.
Determining the inheritance pattern of autosomal dominant disorder:
- The autosomal recessive disorder would be shown by those individuals who have even a single copy of the disease-causing dominant allele.
- There are no carriers/heterozygotes for autosomal dominant disorders.
- It appears in both the sexes with an equal frequency.
- The disease does not skip a generation.
- When one parent is affected and the other one is unaffected, one-half of the offsprings will be affected by the autosomal dominant disease.
- Unaffected parents do not pass the disorder.
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