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Specialised Junctions between Epithelial Cells is considered one of the most asked concept.
14 Questions around this concept.
The function of the gap junction is to :
Epithelial cells are connected by the intercellular junctions which are as follows
1. Tight junctions: Plasma membranes of two epithelial cells in the apical parts are fused together to form tight junctions. These check the flow of materials between the cells.
2. Gap junctions: These are responsible for the exchange of chemicals between adjacent cells.
3. Adhering junctions: These act like cement to keep neighbouring cells together. These are of three types
(a). Zonula adherens: These are dense plaque-like structure towards the cytoplasmic side of each plasma membrane from which fine microfilaments are extended into the cytoplasm.
(b). Desmosomes: These are also plaque-like thicker and stronger junctions with microfilaments of keratin protein. These microfilaments are called tonofibrils. This anchor the cells.
(c). Hemidesmosome: These are similar to desmosomes, but the thickening of the cell membrane is seen on one side only. These join epithelial cells to the basal lamina.
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