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Chargaff Rule MCQ - NEET Practice Questions with Answers

Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET

Quick Facts

  • Chargaff Rule is considered one the most difficult concept.

  • 14 Questions around this concept.

Solve by difficulty

A segment of DNA has 120 adenine and 120 cytosine bases. The total number of nucleotides present in the segment is 
 

In DNA if percentage of Adenine is 30 then what is the percentage of Cytosine?

 In DNA guanine is 10%. The content of adenine is
 

When an RNA molecule contains 15% adenine, how much cytosine will there be?

If DNA percentage of Adenine is 35%, what will be the percentage of Cytosine ?

Denaturation profiles of DNA are shown below. The differences in the profiles arise because

Considering that the reported proportion of adenine bases in a DNA sample is 18%, identify the true statement regarding the composition of other bases in the sample.


 

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If Adenine makes 30% of the DNA molecule, what will be the percentage of Thymine, Guanine, and Cytosine in it?
 

If a double-stranded DNA has 15% cytosine, what is the % of adenine in the DNA? 

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Concepts Covered - 1

Chargaff Rule
  • Erwin Chargaff provided the rule for base equivalence that formed the backbone of the proposition of the structure of DNA given by James Watson and Francis Crick.
  • It states that when the DNA from a particular species is subjected to hydrolysis to release its components of purines and pyrimidines, the following would be observed:
    • The total amount of adenine released is equal to the total amount of thymine. Similarly, the total amount of cytosine released is equal to the total amount of guanine.
    • The base ratio A/T = 1 and C/G = 1.
    • So, A/T = C/G = 1, So, A + G = T + C 
  • Chargaff’s rule allows the determination of percent of all the bases present in the DNA sample if we know the percent of any one of the bases.
  • The rule does not apply to single-stranded DNA genomes as well as to mitochondrial genome.
     

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Chargaff Rule

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