Introduction:
- A cell is the unit of a living thing.
- A living thing can be made up of one cell like a bacterium of many cells like a human. Irrespective of the number of cells, living things are referred to as organisms.
- Hence, the cell is the basic unit of an organism.
- A cell can be defined as the basic structural and functional unit of life.
- It is called the structural unit because it forms the body/structure of the organisms.
- It is called the functional unit because each cell is capable of performing the essential metabolic functions.
Discovery of Cell:
- In 1665, Robert Hooke first discovered the cell using his self-designed microscope. He observed the dead cells of cork of plants. He described his observation as empty cells and termed them as ‘cells’.
- In 1674, the documentation of live cells was made by Anton van Leeuwenhoek, who observed bacterial cells and algal cells.
Cell Theory:
- In 1838, the German botanist Matthias Schleiden observed that all plants are made up of cells.
- In 1839, the German zoologist Theodor Schwann declared that all animals are composed of cells.
- These observations laid the foundation of the Cell Theory.
- Later, the German physician Rudolf Virchow stated Omnis cellula e cellula, that is, new cells arise from pre-existing cells.
Based on these observations, the cell theory can be stated as:
- All living organisms are made up of one or more cells.
- Cells are the basic unit of structure and function of organisms.
- Cells come only from preexisting cells because cells are self-reproducing.
As technology advanced, the insight into the cells became clearer and the cell theory got modified as follows:
- All known living things are made up of cells.
- The cell is the structural and functional unit of all living things.
- All cells come from pre-existing cells by division.
- Cells contain hereditary information which is passed from cell to cell during cell division.
- All cells are basically the same in chemical composition.
- All energy flow (metabolism & biochemistry) of life occurs within cells.
Exceptions to Cell Theory:
There are following three exceptions to the postulates of cell theory:
- Viruses are acellular organisms. They are neither considered living nor non-living because they are metabolically dead when not in the host’s cell and live as soon as they enter the host cell. Also, they cannot reproduce on their own.
- Semi-autonomous organelles in eukaryotic cells, that is, mitochondria and plastids have their own genetic material. They can divide on their own while being in the cell.
Cell Size and Shape:
- Cells are microscopic. Mycoplasma (Smallest cells) measure only 0.3 μm in length.
- Bacterial cells have a size of 3 to 5 μm.
- Human red blood cell is 7.0 μm in diameter.
- Egg of the ostrich is the largest isolated single cell.
- The shape of the cell depends on the function it performs.