- The secretion of salivary glands is called saliva.
- The secretion of saliva is called salivation.
- Saliva is essentially (95.5 per cent) water.
- The remaining 4.5 per cent is a complex mixture of ions, glycoproteins, enzymes, growth factors, and waste products.
- The most important ingredient in saliva from the perspective of digestion is the enzyme salivary amylase, also called ptyalin, which initiates the breakdown of carbohydrates.
- Bicarbonate and phosphate ions function as chemical buffers, maintaining saliva at a pH between 6.85 and 7.4.
- Salivary mucus helps lubricate food, facilitating movement in the mouth, bolus formation, and swallowing.
- Saliva contains immunoglobulin A, which prevents microbes from penetrating the epithelium, and lysozyme, which makes saliva antimicrobial.
Regulation of Salivation:
- The sympathetic nervous system reduces salivation
- The parasympathetic nervous system increases salivation
- Chloride ions are also responsible for salivation
TIP
- Paralysis of the facial nerve or the Bell’s palsy causes permanent hyposalivation.
- Xerostomia is the condition of dry mouth resulting due to hyposalivation.
- Sialolithiasis is the obstruction in the salivary ducts.
- Drooling is the uncontrolled flow of saliva outside the mouth.
- Sjogren’s disease is an autoimmune disorder of the destruction of Salivary Glands
NOTE : Parotid is the largest Salivary gland but maximum amount of Saliva is by the Submandibular gland.