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Cell-Mediated Immune System MCQ - Practice Questions with Answers

Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET

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  • Cell-Mediated Immune System is considered one of the most asked concept.

  • 1 Questions around this concept.

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Cell-Mediated Immune System

 

  • It is the second type of acquired immune system.
  • The T-lymphocytes mediate cell-mediated immunity.

Types of T-cells and their Functions:

  • Helper T-cells (TH Cells):
    • These are most numerous of the T cells. 
    • They help in the functions of the immune system. 
    • They produce a growth factor that stimulates В-cell proliferation and differentiation and also stimulates antibody production by plasma cells.
    • They enhance activity of cytotoxic T cells.
  • Cytotoxic T-cells (TC Cells):
    • These cells are capable of killing microorganisms and even some of the body’s own cells directly hence they are called killer cells. 
    • After binding, the cytotoxic T cell secretes hole-forming proteins, called perforins, that punch large round holes in the membrane of the foreign cell.
    • In addition, the cytotoxic T cell releases cytotoxic substances directly into the foreign cell. 
  • Memory T-Cells:
    • These cells are also formed by T-lymphocytes as a result of exposure to antigen and remain in the lymphatic tissue (e.g., spleen, lymph nodes). 
    • They recognize original invading antigens even years after the first encounter. 
    • Suppressor Cells (Regulatory T-cells):
    • These cells are capable of suppressing the functions of cytotoxic and helper T-cells. 
    • They also inhibit the immune system from attacking the body’s own cells. 
  • Natural Killer (NK) Cells:
    • NK cells attack and destroy target cells, participate in antibody dependent cell-mediated cytotoxicity. 
    • They can also attack parasites which are much larger than bacteria.


 

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