Vaccination is a process by which specific antibodies are developed in a normal man to immune the body from specific diseases caused due to pathogens.
A preparation of antigenic proteins of pathogen or inactivated/weakened pathogen (vaccine) is introduced into the body.
The antibodies produced in the body against these antigens would neutralize the pathogenic agents during actual infection.
The vaccines also generate memory – B and T-cells that recognize the pathogen quickly on subsequent exposure and overwhelm the invaders with a massive production of antibodies.
Immunization is the process by which the body produces antibodies against vaccine-preventable diseases through the administration of specific vaccines.
Vaccination provides immunization after a time period.
So passive immunization is practiced in such cases where prepared antibodies, antitoxins and antivenoms are injected to the patients. Ex. Tetanus, Snake bite.
Recombinant DNA technology has allowed the production of antigenic polypeptides of pathogens in bacteria or yeast.
Vaccines produced using this approach allow large scale production and hence greater availability for immunisation, e.g., hepatitis B vaccine produced from yeast.