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    4. Bohr's Effect on Oxygen Dissociation Curve MCQ - Practice Questions with Answers

    Bohr's Effect on Oxygen Dissociation Curve MCQ - Practice Questions with Answers

    Edited By admin | Updated on Sep 18, 2023 18:34 AM | #NEET

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    Bohr’s effect is

     

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    Bohr's Effect on Oxygen Dissociation Curve
    • The effect of carbon dioxide and pH on the oxygen dissociation curve is called the Bohr’s effect.
    • CO_{_{2}} is a major by-product of cellular metabolism. 
    • It is a nonpolar molecule and so it does not dissolve in the blood.
    • To increase its solubility, carbonic anhydrase converts the CO_{_{2}} into carbonic acid in the presence of water. 
    • Carbonic acid is a weak acid and it dissociates into bicarbonate and hydrogen ions that are soluble in blood.
    • As the concentration of hydrogen ions increases in the blood, the pH becomes acidic, affecting the oxygen binding with haemoglobin. 
    • Hydrogen ions bind to the haemoglobin at an allosteric site and the curve shifts to the right.

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