The major function of bones is to support various organs of the body
Bones contain inorganic substances like phosphate, calcium carbonate, calcium fluoride, magnesium phosphate etc.
Decalcified bone: A bone whose inorganic part has been dissolved and the organic part remains is called decalcified bone.
Dry bone: A bone whose inorganic matter is intact while the organic matter has been destroyed.
The bone tissue is made up of cells, matrix and fibres like any other connective tissue.
The matrix or ground substance of bone is made up of organic as well as inorganic substances. Hydroxyapatite is responsible for providing the compressive strength while collagen fibres are responsible for providing tensile strength.
The mesenchymal cells differentiate into osteoblasts.
Osteoblasts are responsible for making the bone tissue by secreting the ECM and fibres.
The Osteoblasts then differentiate into osteocytes. These are present within the lacunae.
There is a third category of cells called osteoclasts. These are the type of macrophages that resorb the bone tissue and release calcium and phosphate in the blood.
Structural Unit of Bone - Osteon
The basic unit of the structure of bone is called osteon.
An osteon is made up of concentric rings of the matrix. These rings are called Lamellae.
The osteocytes are present alongside the lamellae within the lacunae.
Each osteocyte is connected to the other osteocyte through the canaliculi with the help of processes or extensions.
In the centre of the osteon, there is a canal called the Haversian canal.
Haversian canal contains blood vessels, lymph vessels and neurons.
There are many individual osteons in a characteristic compact bone.
Haversian canals are connected to each other via the Volkmann’s Canal.