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INI CET Most Expected Questions 2026: High-Yield MCQs with Answers
INI CET Most Expected Questions 2026: Nobody can tell you the exact questions that will come in the INI CET exam. What we can do is look at what has been repeated and practise those. The INI CET January 2027 session is on November 1, 2026, so the last few days should go to high-yield topics, not new chapters. This article lists the most expected INI CET questions for 2026, built from topics that keep coming back in INI CET previous years' papers. Use them for last-minute revision, to find weak areas, and to get used to the clinical, image-based and case-based style AIIMS asks.
This Story also Contains
- INI CET Most Expected Questions 2026: How We Picked Them?
- INI CET Most Expected Questions 2026: Why These Chapters?
- INI CET Most Expected Questions 2026: Questions That Came Back More Than Once
- Biochemistry and Pharmacology
- Medicine
- Surgery and Pathology
- Microbiology
- Obstetrics and Gynaecology
- How to Use Most Expected INI CET Questions List
INI CET Most Expected Questions 2026: How We Picked Them?
The exam is a computer-based test of 200 MCQs in 3 hours, with +1 for a correct answer and −⅓ for a wrong one. With so many questions and negative marking, your best use of the last days is to revise what keeps coming back.
How we picked them. We classified 963 questions from five past papers. We took them from chapters that appeared in at least four of the papers (Genetics, Neurology, Cardiology, Pulmonology, Obstetrics, Gynaecology, General Pharmacology, Neoplasia, GI Surgery, Endocrine Surgery and Systemic Bacteriology), and from the few questions that repeated almost word for word. We then checked each answer against standard teaching and dropped any key we were not comfortable with.
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INI CET Most Expected Questions 2026: Why These Chapters?
Evidence from the papers | Number |
Question stems compared across papers | about 1,000 |
Questions repeated almost word for word | 4 |
Chapters that appeared in all five papers | 14 |
Obstetrics and Gynaecology questions in four papers | 74 |
Genetics questions in four papers | 18 |
Repeated questions are rare, but repeated chapters are not. So the questions below are best used as a map of what examiners like to ask, not as a list to memorise.
INI CET Most Expected Questions 2026: Questions That Came Back More Than Once
These appeared in more than one paper with the same answer.
Which is the most effective drug for smoking cessation?
A. Varenicline
B. Buspirone SR
C. Nicotine gum
D. Rimonabant.
Answer: A. (Seen in July 2021, November 2021 and the second 2022 paper.)
What is the repair mechanism associated with CRISPR-Cas9?
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B. Base excision repair
C. Nucleotide excision repair
D. Mismatch repair.
Answer: A. (Seen in both 2021 papers.)
What is the mechanism of action of cyclosporine?
A. Inhibition of calcineurin
B. AMP kinase stimulation
C. IMP dehydrogenase inhibition
D. Dihydro-orotate dehydrogenase inhibition.
Answer: A. (Seen in both 2021 papers.)
Biochemistry and Pharmacology
Which method is used to detect RNA?
A. Sanger's method
B. G banding
C. Western blot
D. RT-PCR.
Answer: D.
The wobble hypothesis explains which concept of the genetic code?
A. Universal
B. Unambiguous
C. Degeneracy
D. Non-punctuated.
Answer: C.
miRNA binds to which part of mRNA to inhibit translation?
A. Gene body
B. Gene promoter
C. 3'UTR
D. 5'UTR.
Answer: C.
What is the effect of RNAi on gene expression?
A. Knock out
B. Knockdown
C. Knock up
D. Knock in.
Answer: B.
If the dose of a first-order drug is doubled, what happens to half-life and plasma concentration?
A. Half-life doubles, concentration unchanged
B. Half-life unchanged, concentration doubles
C. Both unchanged.
Answer: B.
The elimination rate constant of a drug is 0.05/hr. What is its half-life?
A. 20.8 hours
B. 6.9 hours
C. 13.8 hours
D. 9.8 hours.
Answer: C.
At what dopamine dose does it act on beta-1 receptors?
A. 2–10 mcg/kg/min
B. <2 mcg/kg/min
C. 10–20 mcg/kg/min
D. >20 mcg/kg/min.
Answer: A.
Which drug increases the bioavailability of saquinavir?
A. Ritonavir
B. Vitamin C
C. Cimetidine
D. Ganciclovir.
Answer: A.
Medicine
For the diagnosis of resistant hypertension, the patient must be on three drugs including at least one:
A. Calcium channel blocker
B. Beta-blocker
C. Alpha blocker
D. Diuretic.
Answer: D.
Which drug is not used for emergency management of hyperkalaemia?
A. 10% calcium gluconate
B. Salbutamol nebulisation
C. Insulin-dextrose
D. Injection MgSO₄.
Answer: D.
Which is not a cause of central cyanosis?
A. Methaemoglobinaemia
B. Pulmonary arteriovenous fistula
C. High altitude
D. Hypothermia.
Answer: D.
Treatment of choice for an acute attack of cluster headache:
A. Oral sumatriptan
B. Subcutaneous sumatriptan
C. 100% oxygen at 6 L/min
D. 100% oxygen at 8 L/min.
Answer: B.
A woman on mechanical ventilation for ARDS has PaO₂ 50 mmHg despite FiO₂ of 90%. Next step?
A. Reduce FiO₂
B. Increase tidal volume
C. Increase respiratory rate
D. Increase PEEP.
Answer: D.
An increased anion gap is seen in:
A. Respiratory acidosis
B. Respiratory alkalosis
C. Metabolic acidosis
D. Metabolic alkalosis.
Answer: C.
Surgery and Pathology
Appendicectomy by a gridiron incision is converted to a Rutherford Morrison incision. Which muscles are cut?
A. External oblique, transversus, rectus
B. Internal oblique, transversus, rectus
C. External oblique, internal oblique, transversus
D. External oblique, internal oblique, rectus.
Answer: C.
Which vaccine is not recommended before splenectomy?
A. Pneumococcal
B. Typhoid
C. Haemophilus influenzae
Answer: B.
The most common ectopic tissue in Meckel's diverticulum is:
A. Gastric and pancreatic
B. Colonic and pancreatic
C. Gastric and colonic
D. Thyroid and lung.
Answer: A.
For which HER2/neu result is FISH required?
A. 1+
B. 2+
C. 3+
D. All.
Answer: B.
A boy has fever, night sweats and neck swelling, and the biopsy shows a starry-sky appearance. Which genetic abnormality?
A. MYC
B. RAS
C. BCR-ABL
D. p53.
Answer: A.
HPV inactivates the RB gene through which protein?
A. E6
B. E7
C. L1
D. L2.
Answer: B.
Microbiology
Foul-smelling discharge with yellow granules after tooth extraction; gram-positive filamentous rods. Likely pathogen?
A. Chromoblastomycosis
B. Mucormycosis
C. Actinomyces israelii
D. Histoplasmosis.
Answer: C.
Muscle spasms with an arched back after a puncture wound. Toxin mechanism?
A. Presynaptic inhibition of GABA and glycine release
B. Presynaptic inhibition of ACh receptors
C. Postsynaptic inhibition of GABA
D. Cleavage of SNARE proteins.
Answer: A.
Obstetrics and Gynaecology
A primigravida in labour: posterior cervix, 5 cm cervical length, 1 cm dilatation, soft consistency, head at −1. What is the Bishop score?
A. 8
B. 5
C. 3
D. 0
Answer: B.
What is the dose of carbetocin for prevention of postpartum haemorrhage?
A. 50 mcg
B. 150 mcg
C. 200 mcg
D. 100 mcg.
Answer: D.
How to Use Most Expected INI CET Questions List
Attempt without options first. Say the answer, then look at the choices.
Revise the idea behind each answer. For example, after question 22, revise all MYC-related tumours.
Then go wider. Build your plan from the syllabus and practise with the INI CET previous year papers.
Guess carefully. Guess only after removing options, because wrong answers cost ⅓ mark.
Check the answers yourself. The keys come from the papers. Confirm anything doubtful in a standard textbook.
Also Read:
Frequently Asked Questions (FAQs)
Q: Can anyone predict the exact INI CET 2026 questions?
A:
No. This list is a set of past questions from chapters that kept repeating, chosen by us as practice. It is not a prediction.
Q: Are INI CET questions repeated?
A:
Individual questions rarely repeat. In our check of about 1,000 stems, four came back almost word for word. Chapters repeat much more often.
Q: Is there negative marking in INI CET?
A:
Yes. Each correct answer gives +1, each wrong answer deducts ⅓ of a mark, and unanswered questions score zero.
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Have a question related to INI CET ?
Hello there,
If your provisional registration expired in July 2026, you should get it renewed or obtain your permanent registration as soon as possible. An expired registration may create an issue during document verification or admission.
You can still check your INI-CET eligibility for the relevant session. Still, I strongly
You can download the INI CET previous year papers from the link given below:
Hello Student,
INI SS Round 2 seat allotment was released on July 9. I am sharing a link where you can find the seat allotment list and other details.
Article Link - INI SS July 2026 Counselling Round 2 Seat Allotment Result OUT: Direct Link.
Hello Aniket,
Please refer to the given link to access the INI-CET solved previous year question papers. In this article, we have provided all the previous years' question papers in one place for your convenience.
Hope this helps!
Hello Dear Student,
For the May 2026 session (conducted in July 2025, results released May 23, 2026), the Round 1 cutoff rank for the ST category is 31,313 .
-
January 2026 Session (Round 1 ST Cutoff): 27,569
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May 2026 Session (Round 1 ST Cutoff): 31,313
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